A Hidden Paradox in Carcinogenesis Bioassays

The Paradox of Infectious Diseases in India Kumarakom-a Hidden Gem

Concordance between rats and mice in bioassays for carcinogenesis.

According to current policy, chemicals are evaluated for possible cancer risk to humans at low dose by testing in bioassays in which high doses of the chemical are given to rodents. Thus, risk is extrapolated from high dose in rodents to low dose in humans. The accuracy of these extrapolations is generally unverifiable because data on humans are limited. However, it is feasible to examine the a...

Studying humane endpoints in a rat model of mammary carcinogenesis

Objective(s): The present work intended to clearly define the most adequate humane endpoints in an experimental assay of mammary carcinogenesis in rats. Materials and Methods: Animals were observed twice a day; all parameters were registered once a week and the euthanasia endpoints were established in order to monitor the animal welfare/...

A paradox: Midwives’ Experiences of Attending a Birth Resulting in Maternal Death in a Ghanaian Context

Background & aim: In a lower-middle income country, such as Ghana, maternal death still occurs even in case of providing skilled perinatal care. The impact of maternal death on the family, community, and society has been largely studied. However, its implications for midwifery practice in Ghana has not been extensively investigated. The purpose of this study was to exp...

Hidden Fetus in Fetu in a Male Adult

We present unusual retained remnants of hidden conjoined twin of possible abdominal pagus after 21 years who presented with abdomenpain and incidentally have found his forbidden conjoined twin. He presented for many years with a palpable epigastric mass, and recent abdominal pain, early satiety, nausea and vomiting. The mass was a like deformed fetus weighing 815 gr who was anencephalic and dep...